CONP Portal | Dataset


Alzheimer’s mouse models dataset
Creators: Dr. Marco Prado, Dr. Boyer Winters
Contact: Sara Memar, smemarko@uwo.ca
Licenses: CC0
Version: 1
Formats: CSV
Size: 100.0 MB
No of Files: 16
No of Subjects: 652
Primary Publication: MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment. Flavio Beraldo et al. eLife. https://elifesciences.org/articles/49630
Metadata file: DATS.json
Is About: Mus musculus
Acknowledges: Weston Brain Institute, Canada First Research Excellence Fund, Canadian Open Neuroscience Platform
Description:
This dataset has data files from 5-Choice, Pairwise Visual Discrimination (PVD), and Paired-Associates Learning (PAL) cognitive behavioral tasks in which male and female mice from 3 Alzheimer’s mouse models were tested using touchscreen technology at two different sites (e.g. University of Western Ontario and University of Guelph). Both aggregated data and trial-by-trial data are provided in this dataset.

Dataset README information

README.md

Weston-Project: Alzheimer’s mouse models dataset

This dataset has data files from 5-Choice, Pairwise Visual Discrimination (PVD), and Paired-Associates Learning (PAL) cognitive behavioral tasks in which male and female mice from 3 Alzheimer’s mouse models (3xTG-AD, 5XFAD, APP/PS1) were tested using touchscreen technology at two different sites (e.g. University of Western Ontario and University of Guelph). Both aggregated data and trial-by-trial data are provided in this dataset.

COMMON METADATA:

Dataset type: Cognitive Behavioral Data from Touchscreen Technology

Source: https://mousebytes.ca

DOI: https://doi.org/10.7554/eLife.49630

Animal Specie: Mouse

Animal Sex: Female, Male

Animal age (month): "3-6", "7-10", "11-14"

Animal strain: 3xTG-AD, 5XFAD, APP/PS1

Animal Genotype: 3xTG-AD, 5XFAD, APP/PS1, B6129SF2/J, B6SJLF1/J, C57BL/6J

Housing: Single-housed

Light Cycle: Diurnal light cycle

Intervention: N/A

AGGREGATED DATA:

File Name: FB_AD_5Choice.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=3e55d56e-08e1-431b-98e9-f649db1a6ce5

Cognitive Task: 5_Choice

Aggregation Function: Mean

Trial by Trial: No

File Name: DP_AD_5Choice.csv

PI: Dr. Boyer Winters, University of Guelph

Data Link: https://mousebytes.ca/data-link?linkguid=f076dc4d-7c9a-48cb-a361-36c7315d0e7e

Cognitive Task: 5_Choice

Aggregation Function: Mean

Trial by Trial: No

File Name: FB_AD_PD.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=0e45db27-70f6-4702-8ddd-8865c6f2d4d5

Cognitive Task: Pairwise Visual Discrimination (PVD)

Aggregation Function: Mean

Trial by Trial: No

File Name: DP_AD_PD.csv

PI: Dr. Boyer Winters, University of Guelph

Data Link: https://mousebytes.ca/data-link?linkguid=b1fa03d7-8d41-49c9-8962-86894078b8c6

Cognitive Task: Pairwise Visual Discrimination (PVD)

Aggregation Function: Mean

Trial by Trial: No

File Name: FB_AD_PAL_Analysis.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=1c3c90f7-020f-42cf-837b-fe1d00a13e54

Cognitive Task: Paired-Associates Learning (PAL), Analysis

Aggregation Function: Mean

Trial by Trial: No

File Name: FB_AD_PAL_Acquisition.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=55ba0822-b8b0-409f-96e9-85aa94f4a0b2

Cognitive Task: Paired-Associates Learning (PAL), Acquisition

Aggregation Function: Mean

Trial by Trial: No

File Name: DP_AD_PAL_Analysis.csv

PI: Dr. Boyer Winters, University of Guelph

Data Link: https://mousebytes.ca/data-link?linkguid=3894eb3e-fe07-4898-a5cc-f2619a3873c5

Cognitive Task: Task: Paired-Associates Learning (PAL), Analysis

Aggregation Function: Mean

Trial by Trial: No

File Name: DP_AD_PAL_Acquisition.csv

PI: Dr. Boyer Winters, University of Guelph

Data Link: https://mousebytes.ca/data-link?linkguid=8c01c6bb-f0fe-4393-b34f-37e2c39c0151

Cognitive Task: Task: Paired-Associates Learning (PAL), Acquisition

Aggregation Function: Mean

Trial by Trial: No

TRIAL BY TRIAL DATA:

File Name: FB_AD_5Choice_Trial.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=50fcdb9c-d064-413a-8b1e-7a3dc6fc2636

Cognitive Task: 5_Choice

Aggregation Function: N/A

Trial by Trial: Yes

File Name: DP_AD_5Choice_Trial.csv

PI: Dr. Boyer Winters, University of Guelph

Data Link: https://mousebytes.ca/data-link?linkguid=24ebbc94-7673-49e1-92c1-031e84d418c3

Cognitive Task: 5_Choice

Aggregation Function: N/A

Trial by Trial: Yes

File Name: FB_AD_PD_Trial.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=ca83d7bd-9551-4fe8-819e-1c7a4f4e4d22

Cognitive Task: Pairwise Visual Discrimination (PVD)

Aggregation Function: N/A

Trial by Trial: Yes

File Name: DP_AD_PD_Trial.csv

PI: Dr. Boyer Winters, University of Guelph

Data Link: https://mousebytes.ca/data-link?linkguid=950d287f-1a7f-4c02-a7e9-bc1deae7c150

Cognitive Task: Pairwise Visual Discrimination (PVD)

Aggregation Function: N/A

Trial by Trial: Yes

File Name: FB_AD_PAL_Analysis_Trial.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=156bbe12-6cc2-410c-96dd-d9f5e559d7c0

Cognitive Task: Paired-Associates Learning (PAL), Analysis

Aggregation Function: N/A

Trial by Trial: Yes

File Name: FB_AD_PAL_Acquisition_Trial.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=cc2c457a-17aa-4fed-803f-f00529d417c5

Cognitive Task: Paired-Associates Learning (PAL), Acquisition

Aggregation Function: N/A

Trial by Trial: Yes

File Name: DP_AD_PAL_Analysis_Trial.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=642667b6-e933-43fb-89b6-711b069fea5e

Cognitive Task: Paired-Associates Learning (PAL), Analysis

Aggregation Function: N/A

Trial by Trial: Yes

File Name: DP_AD_PAL_Acquisition_Trial.csv

PI: Dr. Marco Prado, Robarts Research Institute (University of Western Ontario)

Data Link: https://mousebytes.ca/data-link?linkguid=c0e7524e-5c35-4226-bf08-ba6403339c87

Cognitive Task: Paired-Associates Learning (PAL), Acquisition

Aggregation Function: N/A

Trial by Trial: Yes

Download Using DataLad

CircleCI status

The following instructions require a basic understanding of UNIX/LINUX command lines. A subset of open datasets on the Portal are also available through a browser-based download button. The instructions below regard dataset download with the use of DataLad. To install DataLad on your system, please refer to the install section of the DataLad Handbook .

Note: For maximum compatibility with conp-dataset, the CONP recommends versions 3.12+ of Python, 10.20241202+ of git-annex, and 1.1.4+ of datalad.

1) Initiate the CONP dataset

Run the following command in the directory where you want the CONP dataset (conp-dataset) to be installed:

2) Install the mousebytesdataset dataset

To install the mousebytesdataset dataset, run the following commands to move into the "projects" subdirectory under the "conp-dataset" directory (created in the previous step) and run datalad install:

3) Download data from the mousebytesdataset dataset

Now that the dataset has been installed, go into the mousebytesdataset dataset directory.

The files visible after installing the dataset but before downloading (in the next step) are symbolic links and need to be downloaded manually using the datalad get command:

If you run datalad get * command, all the files available in the dataset directory will be downloaded.


For more information on how DataLad works, please visit the DataLad Handbook documentation.